bIOFREEZE Is excellent for all aches and mains and is even better if massaged into the painful areas. It may not be discussed as often as pleasure. But pain, like pleasure, is one of our most universal human experiences. In fact, the Joint Commission recently named pain as the "fifth vital sign"-a condition to be evaluated alongside temperature, pulse, respiration and blood pressure. We have studied pain extensively, so that we can better help you manage it.